Hello,
I actually work for a Cisco project, where I'm responsible to help the Cisco customers to start using Cisco Security Products(FTD, ASA with Firepower, WSA, AMP etc). So I'll be able to explain you how does AMP for Networks work, how to configure ACP, File, Intrusion policies. Will provide you the common practices and so on. We will use the latest version of Firepower 6.2.3.
Could you clarify, please, if you have FMC to manage your devices or you are going to use FDM (local on-box management).
Let's see how I can help you...
BR,
Kirill