Simple R project on genes

$10-30 USD

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投稿日:

約6年前

$10-30 USD

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Hello!! I have this basic project on R and I would like it in 22:30 gmt+2 :) DESCRIPTION You are given a dataset ([login to view URL]) concerning genes encoding subunits of proteasome, a cell complex responsible for the degradation of waste proteins. You are also given the ideal ACTTCCG pattern for identifying DNA from a transcription factor TF -X. DELIVERABLES [login to view URL] uploading the dataset to R, locate possible recognition areas from TF-X (ideal pattern) with a maximum deviation of 1 nucleotide. [login to view URL] build Position Weight Matrix (pwm) as shown in the lesson. [login to view URL] this matrix build the appropriate sequence logo. [login to view URL] the generated chart evaluate which of the nucleotides is most important in regulation of gene expression by TF-X. [login to view URL] your answer. [login to view URL], plot the heatmap in the following example: image (t (matrix (c (1,1,1,0,0,0,0,0,0), nrow = 3))) [login to view URL], based on the pwm of 1, check the second dataset ([login to view URL]) for its existence of the same pattern. The second dataset concerns genes that regulate apoptosis, a process of programmed cell death. [login to view URL] here also the heatmap. [login to view URL] do you notice? [login to view URL] think that TF-X affects the expression of apoptosis genes? DO NOT USE THE READY PWM FUNCTION IT IS FORBIDDEN! I ATTACH the zip with the 2 txt needed from description. Thank you for your time and looking forward working on this on :)

R Programming Language

Statistical Analysis

プロジェクト ID: 16401188

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7個の提案

リモートプロジェクト

アクティブ 6年前

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この仕事に7人のフリーランサーが、平均$122 USDで入札しています

@shivampanchal

I have a good hands on working with Advanced Excel, R and Python. I have quite a good knowledge of deep learning Algorithm , have also developed dashboards and Shiny Web Application in R I understand the project requirement and will deliver the desired product within the time specified.

$50 USD 1日以内

5.0

(47 レビュー)

6.1

@sumbali

I'm an Engineer in Statistics and Applied Economics, i've got many skills and expertise that will allow me achieving perfectly all the projects and assignments because my priority is your satisfaction I am a master of softwares like SPSS, SAS, STATA, R, Eviews, Minitab, MS excel I have advanced knowledges in: Econometrics: Panel Data, Pooled Data, cross-section Data, Probit, Logit, Multinomial Logit, scoring, Economics modeling, Tobit, Heckman.. ---Data Mining: Factor analysis, Principal Component Analysis, Regression (Simple, Multiple, logisitic, hierarchical, Poisson), PCA, PCA, Data Quality, Data Reliability, ANOVA, ANOM, ANCOVA, Clustering, Hierarchical Clustering and bayesian analysis I'll provide you perfect reporting using MsWord.

$100 USD 3日以内

4.8

(83 レビュー)

6.1

@mohamedrdait

Hello I am an engineer in operational research and decision support I master r programming, statistics clustring machine learning data mining please contact me for more details about the project or for an interview so you can be sure for my high level in r and statistics bst regards

$50 USD 1日以内

4.9

(33 レビュー)

5.1

@sheak

Hello! Being one of the most experienced Statistician/Mathematician on this website with around half thousand excellent reviews and proven track record, I would love to work on this project. I am experienced data analyst also familiar with almost all statistical softwares including SPSS, R, Stata, Eviews, Mathematica, SAS, Weka, Minitab, Python and Matlab etc. Please reply back to discuss further. Thank you!

$222 USD 7日以内

4.8

(7 レビュー)

5.1

@Jinxuetian

Hi I'll help you to complete it, as a skilled R programmer (R Programming Language, Statistical Analysis). Thank you.

$333 USD 10日以内

0.0

(0 レビュー)

0.0

@CodingEnthusiast

Hi, this task looks like one of those typical weekly labs during my Master studies - we had to do various bioinformatics tasks, for instance to align sequences by hand and computationally, make SQL queries, use regular expressions in Python to search for protein motifs or transcription recognition sites, etc. Later, I performed many of these tasks in R as part of my daily work routine. It would be great to get to see the study materials so that I use the exact same method. If this is not an option, I am definitely ready do it my way. I did not understand exactly what is the final day when you need to have the project done but I am rather positive than it could be done in less than 2 days. Looking forward to play with R :) Here are the anticipated steps for the pwm task: - identifying and extracting all the sequences that are potential recognition sites - counting the occurrence of each type of nucleotide at each position of the recognition site. A matrix will be obtained with 4 rows (one for each type of nucleotide) while the number of columns would be equal to the length of the recognition site. - normalizing all the values in the matrix by dividing with the number of sequences -the obtained position weight matrix would then be applied to the apoptosis data set by calculating the score of each nucleotide segment with the same length as the recognition site and filtering by a threshold score.

$30 USD 2日以内